Is it downhill from here? Eliminating leukemic stem cells and curing chronic myeloid leukemia.
نویسندگان
چکیده
Patients with chronic phase chronic myeloid leukemia who respond to imatinib have a rapid initial decrease in BCR-ABL transcript levels (α), followed by a slow decline (β). The rate of β decrease is consistent with declining leukemic stem cells and may predict which patients may safely discontinue therapy.
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ورودعنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 17 21 شماره
صفحات -
تاریخ انتشار 2011